Concentrated Haemodialysis Solution B.P (Calcium free): BBC PART A ONLY IN 10 LTR

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Description

  • Patients on chronic dialysis are susceptible to hypocalcaemia and an attempt is made to provide a positive calcium balance to prevent renal osteodystrophy.
  • In the setting of renal failure requiring dialysis, 61% of calcium is not bound to plasma proteins and is in a diffusible equilibrium during hemodialysis. As a result calcium may be lost in a calcium free dialysate up to 40 mg/L (1.0mmol/L).
  • This is be prevented by adding calcium into the dilute dialysate at 1.75 mmol/L or 7.0 mg/dl or giving calcium intravenously at the same rate it is being lost, Reductions in lonized calcium have been linked to increased vascular instability during hemodialysis,
  • Quality dialysis can be done as there is no chance for cross contamination

The compositiort of the dialysis solution is as follows:

PART 1: The acid concentrate (in liquid form) is composed of the following components in each 1000m

1-SODIUM CHLORIDE IP 210GMLTR 210GMLTR

2-POTASSIUM CHLORIDE IP 5 2GMLTR 3-MAGNESIUM CHLORIDE IP 2.8GM/LTR

4-ACETIC ACID UP 9.0GM/LTR

Procedure for use:

Concentrated Haemodialysis Solution (Bi Bag CA Free Type)

Bicarbonate Dialysate is usually produced by mixing punfied water with an Acid Concentrate and a Base Concentrate. Acid Concentrate supplied in liquid form in 10 Ltrs wide jorry cans, while Vial of Base concentrate already fitted in Machine. The acid concentrate (in liquid form) is composed of the following components in in each 1000ml SODIUM CHLORIDE IP 210GMLTR, POTASSIUM CHLORIDE LP 5.2GM/LTR, MAGNESIUM CHLORIDE IP 2.8GMILTR and ACETIC ACID IP BLOGMLTR. The dialy dalysis machine proportions the acid concentrate, the base concentrate and punted water in 1:1.8334 proportions. The final obtained electrolyte concentration of Na’ is 136 mmol/L, K 2.20 mmol Mg050mmol/l, CH,COO is 4.30 mmol C is 100.00 mmol/l and HCO, is 39.00 mmoit This electrolyte concentration stands in the standard range provided by the W.HO for the said purpose. The electrolyte concentration can be tailor made as prescribed by the nephrologists depending on the patient needs.

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